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Crowding can speed up enzyme reactions—until protein droplets become too packed

Our cells are a hotbed of activity, with reactions churning away to keep us alive. But the cytoplasm, where many metabolic reactions take place, is not uniform. Instead, proteins and other molecules cluster together into membraneless compartments, creating distinct, crowded microenvironments for reactions.

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High-speed microscopy captures 3D images of living cells nearly 400 times faster

Researchers at the University of Tokyo have developed a high-speed microscopy technique that captures images so quickly they can be used to make "videos" of the dynamic processes that occur inside living cells.

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Unusual quantum states in six-layer graphene offer clues to superconductivity

Graphene, a material consisting of a sheet of carbon atoms arranged in a honeycomb pattern, has proved promising for various technological applications. Materials in which several layers of graphene are stacked together can exhibit different advantageous properties.

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Long-standing Indigenous practice of adding shells to sand helps young clams withstand ocean acidification

New research from the University of California, Davis, reveals why adding crushed shells to beach sand helps protect shell-making animals—such as clams, oysters and mussels—from the detrimental effects of ocean acidification.

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Confirming altermagnetism: A geometric twist offers experimental proof

For decades, physicists recognized only two types of magnetism that occur in materials without external influence: ferromagnetism and antiferromagnetism. In findings published in Science, a team led by the U.S. Department of Energy's SLAC National Accelerator Laboratory has delivered conclusive experimental proof of a third magnetic phase called altermagnetism.

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Extraterrestrial detection inspired by firefly communications could distinguish alien signals from pulsars

When we think of extraterrestrial intelligence that might be out there among the stars, we tend to think of creatures not too unlike us, though maybe with gray skin, probably bald and with big black eyes. We focus on the familiar, humanoids. But there are many intelligent species on Earth that are nonhumanoid: dolphins, crows, pigs and—with swarm if not individual intelligence—ants and bees. The film "Arrival" conceived of hexapod beings more capable than humans and with a more sophisticated communication system.

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WaterPuzzle uses magnets to model water's hydrogen bonds for hands-on classroom exploration

Water is one of the most essential components of life, and many of its unique properties arise from interactions between its molecules. Hydrogen bonds influence water's physical properties, contribute to the formation of ice crystals and are crucial for normal biological processes. Understanding these interactions is fundamental to chemistry, physics and biology.

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JWST reveals a distant galaxy that may let most of its ionizing radiation escape

Astronomers using the James Webb Space Telescope (JWST) have found evidence that a distant, exceptionally blue galaxy may allow most of its ionizing radiation to escape into space. Known as EBG-1, the gravitationally lensed galaxy is seen at a redshift of 9.244, about 530 million years after the Big Bang. The paper was posted to the arXiv preprint server on Oct. 16.

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Marine fossils in Colombia reveal possible evolutionary transition without mass extinction

A remarkably diverse fossil ecosystem in central Colombia that preserves an unusual overlap between survivors of older Jurassic groups and newer Cretaceous lineages has led researchers at McGill University and the Centro de Investigaciones Paleontológicas (CIP) to recognize a new pattern of large-scale evolutionary transition, one that does not include mass extinctions.

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The genetic cost of being a lazy parent ... if you're a cuckoo finch

African cuckoo finches (Anomalospiza imberbis) are very deceptive birds, or at least the mothers are. They sneak into the nests of other birds, such as prinias and cisticolas, to lay their eggs, then slip away and leave the hosts to raise the chicks.

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Snowfall and clouds may slow East Antarctic ice loss in a warmer world

A new modeling study, published in the journal Nature Climate Change, suggests that the East Antarctic Ice Sheet may be more resilient to extreme long-term warming than previously estimated. Increased snowfall, greater cloud cover and changes in atmospheric circulation could partially offset ice loss—even under very high carbon dioxide concentrations.

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Customizable nanoparticles show potential for delivering personalized cancer vaccines

A nanoscale particle with a unique structure, developed at MIT, holds potential as a customizable delivery vehicle for personalized cancer vaccines. The backbone of the vaccine is a modified, harmless bacteriophage called M13, which forms a nanofiber that can be coated with cancer antigens. By precisely controlling the density of those cancer proteins, the researchers found that they could create a vaccine that prevents the development of colon tumors in mice.

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Scientists find that a 10-millisecond flash could help build more sensitive gas sensors

Nitrogen dioxide is a harmful gas that requires sensitive detection. Researchers used intense light pulses lasting 10 milliseconds to make molybdenum disulfide flakes and anchor isolated metal atoms in one step. Adding platinum improved the material's room-temperature response to nitrogen dioxide, reaching 100.8% at 400 parts per billion and a detection limit of 17.2 parts per billion. This approach could support advanced gas sensors and applications in catalysis and energy technologies.

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Quantum skyrmions outlast entanglement, hinting at more resilient networks

Quantum networks could one day connect quantum computers into more powerful systems and enable new forms of secure communication. But a fundamental obstacle stands in the way: Quantum information is extraordinarily fragile, and the entanglement between particles of light on which such networks would depend is easily disrupted.

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Researchers create light-activated cages for 'protein killer' molecules

Researchers have created a molecular "cage" that keeps protein-degrading drug molecules inactive until they are exposed to low-energy red light. The technology, called RuPHOTACs, controls when and where these molecules become active, which could help scientists develop treatments that destroy specific proteins while limiting unwanted effects elsewhere.

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