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Reporting Live from JPM 2026: Alex Philippidis and Jonathan Grinstein, PhD

In this video our editors took a break from interviewing CEOs, attending corporate presentations, and walking up San Francisco’s famed hills to share some insights about their week at the event—and more broadly, where biopharma now stands and is expected to go in 2026.

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Tiny Nanocourier that Delivers Molecular Packages to Cell Surface Unveiled

Scientists reported new discoveries about the tiny nanocourier machine that delivers essential molecular packages to the cell surface as part of exocytosis, a fundamental cellular process that is essential for maintaining cell health in nearly all eukaryotes.

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Disarming Antibiotic-Resistant Bacteria That Prevent Healing in Chronic Wounds

The results of a preclinical study demonstrated how a common bacterium, Enterococcus faecalis actively prevents wound healing, and suggested how neutralizing this biological process can allow skin cells to recover and close wounds.

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Dormant Cancer Cells Evade Immune System by Changing Shape in Mouse Model

Cancer cells that disseminate from a tumor can enter a period of dormancy that may persist from months to decades before metastasis. Stopping cancer cells from entering a soft biomechanical state could help the immune system clear dormant cancer.

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StockWatch: Sarepta CEO Defends Elevidys as Q4 Sales Fall Short

Sarepta Therapeutics saw its stock skid 11% after the company announced preliminary unaudited 2025 sales results that missed analyst forecasts for its marketed Elevidys® (delandistrogene moxeparvovec-rokl), which reignited the longtime issue of gene therapy safety following the deaths of three Duchenne muscular dystrophy (DMD) patients last year.

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Level Up Nanomedicine Development with High-Throughput Formulation Screening

In this GEN webinar, our expert speakers will show how Nanoworx combines technical expertise with scalable workflows to support the seamless development of nanomedicines from early discovery and design to large-scale production.

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New Single‑Cell Testing Measures How Effectively Antibiotics Kill Bacteria

The method is called Antimicrobial Single-Cell Testing (ASCT). At single-cell resolution, this large-scale live-cell imaging approach quantifies bacterial killing in real-time.

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Bone Marrow Immune Cell Map Boosts Survival, Relapse Prediction in Multiple Myeloma

A comprehensive map of the immune cells in bone marrow from multiple myeloma patients links immune composition to disease aggressiveness, patient outcomes, and treatment development strategies.

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Cause for Progressive Blindness Identified

A large-scale DNA analysis of 5,000 retinitis pigmentosa patients with an unknown genetic cause found both inherited and de novo mutations in multiple variants of RNU genes.

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Cellares and City of Hope Sign Deal to Automate Solid Tumor CAR T Cell Therapy Manufacturing

City of Hope will evaluate Cellares’ Cell Shuttle™ automated manufacturing platform and Cell Q™ automated quality control system to enable high-throughput manufacturing and quality control of its CARpool program.

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Proteomics at Scale: Current Approaches and Emerging Technologies

In this eBook, we explore the pros and cons of emerging and traditional proteomics technologies in terms of coverage and detail.

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Aragen Launches CHOMax Cell Line Development and Manufacturing Platform

Aragen says analytical development, method qualification and Master Cell Bank (MCB) creation are executed within its biologics network and states that GMP drug substance manufacturing is performed under quality processes.

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Boltz PBC Launches with $28M to Democratize AI Platforms for Drug Discovery

MIT researchers are now turning the prolific Boltz series of models into a software company that promotes open science for AI-guided therapeutics.

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Bionova Scientific and Syenex Enter Plasmid DNA Alliance

Bionova Scientific, an Asahi Kasei CDMO, engineered its genetically stable cell line platform to eliminate insertion sequence elements (ISEs), cryptic prophages, and nonessential bacterial genomic regions.

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Organoids Reveal How Pressure and Growth Shape Pancreatic Lumens

Using pancreatic organoids, researchers show that lumen shape is controlled by the balance between cell proliferation, internal pressure, and epithelial permeability, revealing mechanisms relevant to duct development and cystic disease.

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