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'Restoring the joy of eating': Overcoming dysphagia through 3D food printing technology

As South Korea enters a superaged society, the rising number of cancer and chronic disease patients has made "eating well" an emerging national and social challenge. Dysphagia—difficulty swallowing—is particularly common among patients with intractable cancers, including pancreatic cancer, which occurs frequently in older adults.

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Onsite rapid testing leads to decrease in ER visits among long-term care residents

A study led by Sunnybrook Health Sciences Center, Michael Garron Hospital, Humber River Health and the University of Toronto, in partnership with 20 long-term care (LTC) homes across Toronto, has found that onsite rapid testing for respiratory infections results in fewer transfers to the emergency department among LTC residents.

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Immune signals may help predict responses to therapies for difficult-to-treat depression

In a new study, researchers from The University of Texas MD Anderson Cancer Center have uncovered insights that may help explain how rapid-acting antidepressants, such as ketamine and psychedelics, can reduce symptoms of difficult-to-treat depression. The findings may also help identify patients most likely to benefit from these treatments.

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Newly identified mitochondrial plaques provide potential therapeutic target for Alzheimer's disease

Alzheimer's disease is a devastating neurodegenerative disorder affecting millions of people worldwide. Scientists have long known that two hallmarks of the disease are beta-amyloid (Aβ) plaques and neurofibrillary tangles, which damage and kill brain cells over time. A University of Minnesota research team has identified a type of plaque that represents a potential new therapeutic target for Alzheimer's disease. The findings were recently published in Nature Neuroscience.

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Team success can hide individual mistakes

Is failure necessary for learning? In many cases, yes. Scientists have long known that success can reduce how much people learn from their mistakes. But what happens in a team setting, where outcomes depend on more than one person?

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Not all exercise is equal when it comes to metabolic syndrome risk

Not every disease announces itself with obvious symptoms. Some develop quietly, going unnoticed until they begin to take a serious toll on health. Metabolic syndrome (MetS) is one of them. Rather than a single disease, it is a combination of at least three conditions—including high blood pressure, high blood sugar, excess belly fat, high triglycerides and low HDL (good) cholesterol—that together raise the risk of heart disease, stroke and type 2 diabetes.

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New study links exposure to fungicides and insecticides to changes in the age of menarche

Puberty is a process regulated by the endocrine system, and its timing can be altered by environmental factors. Several recent studies point to a trend toward earlier onset of puberty in girls, a phenomenon linked to a complex interplay among genetics, lifestyle and exposure to chemicals capable of interfering with hormones. Among these substances are certain pesticides, widely used in agriculture and present in some everyday foods.

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Press-needle therapy shows potential for pediatric allergic rhinitis

For children with allergic rhinitis (AR), press-needle therapy, especially in addition to medication, is potentially effective in improving clinical response, symptoms and quality of life, according to a review published in the September issue of the International Journal of Pediatric Otorhinolaryngology.

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Eating a wide variety of plants every day could be more beneficial than taking a probiotic

Eating a wide variety of plants every day could be more beneficial to the microbiome than taking a standard probiotic. New research led by scientists from King's College London and ZOE found that consuming a daily blend with more than 30 different plants resulted in increased populations of "favorable" gut bacteria compared with a probiotic control. The work is published in the British Journal of Nutrition.

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AI can accurately detect left ventricular dysfunction from electrocardiograms

Artificial intelligence (AI) analysis of electrocardiogram (ECG) data can simultaneously detect subtypes of left ventricular (LV) dysfunction and heart failure with preserved ejection fraction (HFpEF), according to a study published online July 28 in the Journal of the American Heart Association.

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Why your doctors keep leaving

If it feels harder to keep the same doctor, you're not imagining it. Health care leaders say retirements, burnout and changing workforce expectations are making it complicated to keep experienced clinicians in place.

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Study shows that social inequality exacerbates barriers to physical activity

A 10-year study of residents of São Paulo, Brazil, reveals that leisure-time physical activity is highly unequal and that the gap between social strata is widening. While highly educated white men are exercising more, women from racial minorities with low levels of education have the lowest rates of physical activity during leisure time. In contrast, exercise associated with urban transportation, such as walking to work, is distributed more evenly across different population segments.

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Chromosome-protecting protein may help explain muscle repair and the rarity of muscle cancers

A protein best known for protecting the ends of chromosomes also helps muscle stem cells preserve their identity and repair damaged tissue, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. The findings offer new clues for treating muscular dystrophy and provide new insights into the mechanisms of cancer.

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Microglia reveal sex-specific brain recovery mechanism after ketamine anesthesia

During ketamine anesthesia, the brain's nerve cells fall silent—as consciousness returns, they begin to reconnect. For the first time, researchers at the Institute of Science and Technology Austria (ISTA) have shown that immune cells in the brain play a critical role in this process—with differences between female and male brains. The findings were published in Science Advances.

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For mind and body: Community gathering places may counteract cognitive disability

Community gathering places, where residents lead group activities, have been promoted across Japan as part of long-term care prevention efforts to extend healthy life expectancy. These often involve exercise and social interaction and are meant to help prevent cognitive decline. However, previous studies have reported inconsistent findings regarding their association with cognitive disability.

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