A new approach to defining obesity could help physicians better determine which patients need more intensive treatment by focusing on the effects of excess adiposity on organs and tissues rather than relying primarily on whether a person meets a set of metabolic risk thresholds.
Approximately 850 million people globally (9.1% of the world's population) have chronic kidney disease (CKD). The number of affected individuals has grown steadily during the past 20 years and is on track to continue rising. Existing drugs, such as RAAS inhibitors and angiotensin receptor blockers, are commonly prescribed, but their effectiveness varies from patient to patient. Moreover, these drugs can slow disease progression but cannot stop it.
Illinois researchers made a breakthrough discovery in the fight against liver cancer. Collaborators Lin-Feng Chen, Susan A. Martinis, and graduate student Xiaodan Lin found that decreasing protein levels of leucyl-tRNA synthetase (LARS) impedes liver cancer cell multiplication.
For patients with interstitial cystitis (IC)/bladder pain syndrome (BPS), the combination of platelet-rich plasma (PRP) and low-intensity extracorporeal shock wave therapy (LI-ESWT) shows therapeutic efficacy, according to a study recently published in Frontiers in Bioengineering and Biotechnology.
For children with asthma, exacerbation risk is associated with distinct profiles depending on house dust mite (HDM) sensitization status, according to a study published online July 16 in the International Journal of Occupational Medicine and Environmental Health.
Hyperuricemia independently predicts mortality in chronic kidney disease (CKD), according to a study published online July 13 in the Journal of Clinical Medicine.
A considerable proportion of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit anxiety symptoms, according to a study published in the Journal of Inflammation Research.
Vape devices are flooding teens' bodies with increasingly heavy doses of addictive nicotine, a new study finds. Average urine levels of a key nicotine metabolite, cotinine, nearly tripled among teenagers over a period of a few months in late 2024, researchers report in JAMA Psychiatry.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is significantly associated with eosinophilic esophagitis (EoE), according to a study published online July 22 in the Journal of Gastroenterology and Hepatology.
For patients with metabolic dysfunction-associated steatotic liver disease (MASLD), the association between liver fibrosis and atherosclerotic cardiovascular disease (ASCVD) varies with glycemic status, according to a study published in Hepatology Communications.
An evidence review of international research suggests widespread misconceptions within the medical community about early milk production, pacifiers and breast pumps may be undermining breastfeeding success in the critical first days after birth.
Exposure to secondhand cigarette smoke during the first days of life can cause changes in tooth enamel mineralization without causing visible changes to the teeth. This was demonstrated in an animal model study conducted by researchers at the Ribeirão Preto School of Dentistry at the University of São Paulo (FORP-USP) in Brazil. The results were published in May in the scientific journal Calcified Tissue International.
The main function of CRISPR-Cas systems is to defend bacteria against various threats, including viruses called bacteriophages. Researchers have continued to study all varieties of CRISPR-Cas systems (to date, two classes, seven types and 46 subtypes have been identified) to understand their capabilities.
Emergency departments across the country face a common challenge: how to reduce long wait times without adding more beds, hiring more staff or expanding facilities. New research suggests one answer may be hiding in plain sight—making better decisions about where patients receive care.
A study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by the "la Caixa" Foundation, found no increased risk of miscarriage, stillbirth or major congenital anomalies among women inadvertently exposed to ivermectin from two weeks before conception through the first four weeks of pregnancy. The findings, published in eClinicalMedicine, add to the available evidence on the safety of this antiparasitic drug during the very early stages of pregnancy, although the researchers stress that the number of cases remains too small to warrant changes to current recommendations.
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