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Beyond trial and error: Integrating computation, processing, and AI to design high-entropy alloys

Designing structural high-entropy alloys (SHEAs) means solving a problem with an enormous number of moving parts: which combinations of composition and processing conditions will yield the phases, microstructures, and mechanical properties a given application demands? Because these alloys mix multiple principal elements in comparable proportions, that question spans length and time scales that no single experiment or model can cover on its own.

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Glowing ghoul or chemical tool? The toxic chemistry behind Victorian séances

In November 1857, during a séance in Jersey City, the medium Leah Brown claimed her body produced luminous particles. So intense was the luminosity emanating from her, she recalled in her memoir, that it almost burned her hands. She rinsed her hands under a tap and then pushed them into the damp earth outside.

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'Porous anchor' that strongly bonds dissimilar materials formed simply by coating and drying

The National Institute for Materials Science has developed a technology to strongly bond dissimilar materials by using a porous layer, formed by a solution-coating and drying process, as an anchor. The research team confirm that even materials that are normally difficult to bond together can be bonded with a strength exceeding 7 MPa by adopting a hybrid approach: adhering to one material through chemical affinity and bonding to another via physical interlocking using tiny pores.

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Anyone Can Dock: Molecular docking platform brings protein-binding predictions to smartphones, tablets and computers

A new platform, developed by researchers at the Center for Computational Sciences, University of Tsukuba, in collaboration with Mahidol University, makes molecular docking easier to access, understand, and integrate into experimental research. The work is published in the Journal of Cheminformatics.

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Technician cracks 1,600-year-old mystery to replicate color-changing effect of Roman glass masterpiece

The Lycurgus Cup, a world-renowned 4th-century A.D. artifact housed in the British Museum, is constructed of "dichroic" glass that shifts from jade green in reflected light to ruby red in transmitted light. This means that depending on where the light source is positioned, observers can see the cup displayed in two distinctive, contrasting colors.

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Metal-free magnetic sensor can be safely implanted for wireless monitoring

Researchers in the U.S. and China have created a biocompatible, metal-free magnet that can be safely implanted and generate signals from deep inside the body. Led by Wubin Bai at the University of North Carolina, the team revealed how magnetism can emerge from the rearrangement of atoms in heated carbon nitride, which strengthens the coupling between unpaired electrons.

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Embedded enzymes help plastics break down faster in the deep sea

Scientists have developed a way for certain types of compostable plastic to break down much faster in marine environments, from shallow coastal waters to the deep sea. The breakthrough comes from tiny enzymes embedded in the plastic that help degrade it from within.

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Reusable palladium catalyst enables more direct chemical synthesis

Making complex molecules often means joining smaller chemical building blocks together, a process facilitated by catalysts, compounds that make such reactions possible or speed them up without being consumed themselves. Many widely used reactions also require chemists to modify their starting molecules before joining them. These added chemical "handles" make the molecules reactive, but preparing them means extra steps and, often, additional waste.

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Tiny droplets use pressure to unlock new routes to degradable plastics

Using a new technique, a research group led by Osaka Metropolitan University (OMU) has substantially increased the range of plastics that can be degraded naturally. The study is published in the journal Macromolecules.

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Light-controlled brake makes random molecular motion 300,000 times slower

Molecules are never still. Driven by thermal energy, they are constantly moving through space, while their individual parts also rotate relative to one another. Scientists at IOCB Prague have now shown that random motion within a molecule can be dramatically suppressed. Using light, they can slow down the relative rotation of two different parts of a single molecule by up to five orders of magnitude, paving the way for more complex molecular machines.

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Potential antimalarial compound discovered in institute's microbe collection

Scientists hunting for a new malaria treatment may have found a solution within a historical natural compound collection housed at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology.

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Counteranion captures reactants to boost light-driven chemistry in dilute solutions

Researchers at Kyushu University have developed a photocatalytic system that can selectively capture reacting molecules and hold them close to the active sites that absorb energy from light. This innovation addresses a long-standing challenge of having the photocatalyst maintain a high reaction rate even when the reacting molecules are present at very low concentrations.

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A 'simple recipe' takes some of the guesswork out of mass spectrometry imaging

A small sample of human tissue can hold a remarkable amount of information. Researchers can use it to search for molecular clues associated with cancer, investigate the chemical landscape of the brain or determine where a drug travels after it enters the body. Mass spectrometry imaging, or MSI, helps answer those questions by mapping where different molecules are located within tissue.

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Machine learning simulations reveal how plastic transforms into hard carbon

In a new study published in Chemical Science, researchers from the University of Oxford's Department of Chemistry have used machine learning simulations to trace how a common polymer transforms into hard carbon, revealing the atomic-scale processes that give this technologically important material its disordered structure.

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A 60-year search is over: Chemists isolate long-elusive molecules with boron-oxygen triple bonds

In a new publication in the journal Nature Chemistry, chemists in professor Holger Braunschweig's team at the University of Würzburg, supported by computational work from the team of professor Ashwini K. Phukan at Tezpur University in India, detail their discovery of a method for preparing and isolating a range of surprisingly stable oxoboranes—a challenge that has stood for over 60 years.

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