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Rye pollen's cancer-fighting structure revealed for first time

Nearly three decades ago, scientists found that a pair of molecules in rye pollen exhibited an unusual ability to slow tumor growth in animal models of cancer. But progress stalled for one seemingly simple reason: No one knew exactly what the molecules looked like.

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Sweetening the deal for sustainability, while removing carbon dioxide

Here's a novel pathway to a more sustainable planet: carbo-loading for the public good. In a new study published in Nature Synthesis, chemists at Yale and the University of California-Berkeley have developed a two-step process that removes carbon dioxide (CO2) from the air and converts it into carbohydrates, aka sugars.

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Identifying corrosion initiation sites in aluminum alloys

Researchers at Tohoku University have developed a new technique to identify the initiation sites of a destructive process called pitting corrosion, which occurs when aluminum (Al) alloys are exposed to sodium chloride solutions. This advancement is expected to accelerate the development of Al alloys with improved corrosion resistance. Since Al alloys are widely used in transportation equipment, improving corrosion resistance means we can develop more durable automotive engines, suspensions, and transmissions.

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Study sheds light on the function of a key antibiotic-producing enzyme

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin infections.

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Tuning color through molecular stacking: A new strategy for smarter pressure sensors

Piezofluorochromism, the phenomenon of materials reversibly changing their fluorescent color when pressure is applied, is used to create the pressure sensors used in automotive and medical industries. By monitoring color changes, researchers can visually recognize phenomena, such as chemical changes, that actually take place. However, as devices get increasingly complicated, there is an increasing demand for ways to produce more sensitive sensors.

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AI method advances customized enzyme design

Enzymes with specific functions are becoming increasingly important in industry, medicine and environmental protection. For example, they make it possible to synthesize chemicals in a more environmentally friendly way, produce active ingredients in a targeted manner or break down environmentally harmful substances.

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Study reveals why light-driven chemical reactions often lose energy before bond-breaking

Florida State University researchers have discovered a pathway within a certain type of molecule that limits chemical reactions by redirecting light energy. The study could enable development of more efficient reactions for pharmaceuticals and other products.

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Molecular surgery: 'Deleting' a single atom from a molecule

Inserting, removing or swapping individual atoms from the core of a molecule is a long-standing challenge in chemistry. This process, called skeletal editing, can dramatically speed up drug discovery or be applied for upcycling of plastics. Consequently, the field is witnessing a surge of interest spanning from fundamental chemical research to applications in the pharmaceutical industry.

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Cellulose-based composite sheet exhibits simultaneous adsorption and shielding of radioactive elements

Researchers at University of Tsukuba have developed a cellulose-based composite sheet that integrates paper pulp with starch, polyaniline (a conductive polymer), Prussian blue (a coordination compound), and alginic acid (a natural polysaccharide). These components were assembled into layered structures using a traditional papermaking technique. The resulting sheet exhibits efficient simultaneous adsorption and immobilization of radioactive elements, including cesium, iodine, and strontium.

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Tungsten carbide phase control: Engineering a low-cost alternative catalyst for producing sustainable petrochemicals

Important everyday products—from plastics to detergents—are made through chemical reactions that mostly use precious metals such as platinum as catalysts. Scientists have been searching for more sustainable, low-cost substitutes for years, and tungsten carbide—an Earth-abundant metal used commonly for industrial machinery, cutting tools, and chisels—is a promising candidate.

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The art of custom-intercalating 42 metals into layered titanates

A research team affiliated with UNIST has reported a novel synthesis strategy that enables the direct intercalation of a wide range of metal cations into the interlayer spaces of layered titanate (LT) structures. This approach opens new possibilities for designing highly tailored catalysts and energy storage materials for specific industrial applications.

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Hydrogen's role in generating free electrons in silicon finally explained

Researchers announced that they have achieved the world's first elucidation of how hydrogen produces free electrons through the interaction with certain defects in silicon. The achievement has the potential to improve how insulated gate bipolar transistors (IGBTs) are designed and manufactured, making them more efficient and reducing their power loss. It is also expected to open up possibilities for future devices using ultra-wide bandgap (UWBG) materials.

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Ion accumulation in liquid–liquid phase separation regulates biomolecule localization, finds study

Researchers have identified a new physicochemical principle governing liquid–liquid phase separation in polymer solutions. Their research demonstrates that during the separation of a polymer mixture into two fluid phases, coexisting ions are unequally distributed between the phases. The paper is published in the journal ACS Macro Letters. The team includes Miho Yanagisawa, an associate professor at the University of Tokyo; Hiroki Sakuta, a project assistant professor; Arash Nikoubashman, a Heisenberg Professor at the Leibniz Institute of Polymer Research Dresden; and their colleagues.

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A year after undermining Bredt's rule, scientists make cage-shaped, double-bonded molecules that defy expectations

Organic chemistry is packed with rules about structure and reactivity, especially when it comes to making and breaking chemical bonds. The rules governing how these bonds, which hold atoms together in molecules, form and the shapes they give molecules are often thought to be absolute, but UCLA organic chemists are pushing the boundaries of the possible.

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A new three-way single step rearrangement enables precise ring editing

A new three-way bond-breaking and making mechanism makes the synthesis of five-membered rings easier than before.

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